Express Scripts Holding Co. engages in the provision of integrated pharmacy benefit management services. Its services include network-pharmacy claims processing, home delivery pharmacy care, specialty pharmacy care, benefit-design consultation, drug utilization review, formulary management, and medical and drug data analysis services. It operates through the following segments: Pharmacy Benefit Management and Other Business Operations. The Pharmacy Benefit Management segment includes clinical solutions to improve health outcomes, specialized pharmacy care, home delivery pharmacy services, specialty pharmacy services, retail network pharmacy administration, benefit design consultation, drug utilization review, and drug formulary management. The Other Business Operations segment provides consulting services for pharmaceutical, biotechnology, and device manufacturers to collect scientific evidence to guide the safe, effective, and affordable use of medicines. The company was founded on July 15, 2011 and is headquartered in St. Louis, MO.